? Change dose?

Discussion in 'Prozinc / PZI' started by Peppersmom72, Jan 4, 2018.

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  1. Peppersmom72

    Peppersmom72 Member

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    I've switched Pepper to Prozinc and because it is a low dose, her BG numbers are through the roof.
    When can I change her dose?
     
  2. Djamila

    Djamila Well-Known Member

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    Why did you go down to one unit when you switched? Usually you switch insulins at a comparable dose - just a bit lower, but not all the way back to one unit. At first glance I would say to increase right now, but I'm wondering if there is more to the story that I need to know before I say for sure? And we can also talk about how much to increase.
     
  3. JanetNJ

    JanetNJ Well-Known Member

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    I'd do 2 tomorrow.
     
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  4. Peppersmom72

    Peppersmom72 Member

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    The vet said to start at 2. When I asked on here if that was correct, I was advised to start at 1.
     
  5. Peppersmom72

    Peppersmom72 Member

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    Is it safe to go up a full unit?
     
  6. Djamila

    Djamila Well-Known Member

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    Was that out on the Main Health forum? I'll see if I can find the thread - I'd like to see why that was recommended....
     
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  7. Peppersmom72

    Peppersmom72 Member

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    It may have been. It was within the past week
     
  8. Djamila

    Djamila Well-Known Member

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    Sorry that took so long. You have a lot of threads out there! :)

    Here it is: http://www.felinediabetes.com/FDMB/threads/need-some-help-please.188593/

    I'm guessing from reading through the threads that the one unit was suggested out of caution because it sounds like you're gone for long hours during the day and are somewhat limited in how much you can test. Is that correct?

    In general yes, increasing by a full unit is too much too fast. Though there are times when we recommend it when it's still early like this and the starting dose is just too low. I'm going to tag @Kris & Teasel to weigh in on this since it looks like she's been following your history through a number of your threads and I have only skimmed a bit.
     
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  9. Peppersmom72

    Peppersmom72 Member

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    Ok, thank you. Yes, I've posted alot. I had a lot of questions and this seems the best place to get answers. Everyone is so helpful.
     
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  10. Peppersmom72

    Peppersmom72 Member

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    I can only test AMPS, PMPS and up to +6 after pm insulin. I work an hour and a half away from home. Evenings and weekends is where I do majority of her testing.
     
  11. Djamila

    Djamila Well-Known Member

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    This is a great place, and I'm glad you're posting and asking questions! This is such a great community! I've been on here for a couple of years and still ask questions and seek out other opinions when I'm making decisions. It's a wonderful, caring, smart group of people!
     
  12. Djamila

    Djamila Well-Known Member

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    Oh wow, that's a long commute! I'm guessing that's why it was recommended to start a little lower - just to make sure Pepper is safe. I do think I'd like to see you increase sooner rather than waiting the full week (that's what is usually recommended on the initial dose), but again, let's see what Kris says since she has more history with you.

    Are you around this weekend? If Kris hasn't had a chance to check-in before the morning dose, I'd say go ahead and stick with the one unit in the morning, and then tomorrow is Friday evening so if you're around for the weekend, we can maybe make an adjustment then.
     
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  13. Peppersmom72

    Peppersmom72 Member

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    I will definitely be around this weekend. I can also check my email periodically during the day to see what she responds with. Thank you so much for your help.
     
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  14. Cat guy

    Cat guy New Member

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    Go with 2iu prozinc , her numbers are kinda high:cat:
     
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  15. Rachel

    Rachel Well-Known Member

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    Yep, looks like you're due for an increase! I agree with Djamila...if you do it when you're home to keep an eye on her, it'll be best. I'd do the increase tonight (Friday night) and that way you can keep an eye on things. :) Unless Kris suggest otherwise...she's been following you I see.

    Also, welcome! Ask us any questions you have...we're happy you're here and happy to help!
     
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  16. Peppersmom72

    Peppersmom72 Member

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    Thank you all! I will give Pepper 2u this evening.
     
  17. Peppersmom72

    Peppersmom72 Member

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    I just wanted to express.....

    Wow! these needles are huge for u-40 syringe compared to u-100. lol.
     
  18. Djamila

    Djamila Well-Known Member

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    If you prefer the u100's, they can be used with prozinc if you use the conversion chart:

    http://www.felinediabetes.com/insulin-conversions.htm

    If you decide to go that route, be very careful and play around a bit first to make absolutely certain that you understand how to do the conversion. I use the u100's so I can make more precise changes in dose and not have to guess so much for the in between doses.
     
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  19. Kris & Teasel

    Kris & Teasel Well-Known Member

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    Just seeing this now - needed an early night last night. :) I've reread the previous thread discussing Pepper's inappetance, etc. The 1 u starting dose was suggested because advice givers were being cautious. I like Djamila's suggestion to raise the dose tonight and monitor more on the weekend. You'll be going up a full unit to 2 u which is closer to her required dosing range. Some cats have an initial bigger reaction to a new dose so I'd test her at +2 tonight to see if she's dropping more quickly than usual.

    Keep posting here - small forum and your posts will be seen quickly (usually!).
     
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  20. Djamila

    Djamila Well-Known Member

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    Ah! I missed that there was a history of inappetance too! Thanks so much, @Kris & Teasel! I figured there must be a reason for starting that low. Is that resolved now?

    Do you feel okay about a full unit increase in this case, or do you think a 0.5u would be better? It's still early enough that Pepper hasn't really adjusted to the one unit which makes me think the big increase might not be too bad - coupled with peppersmom72 (I'm sorry, I dont' think I know your name....?) being able to monitor this weekend if she gets bouncy. But since this is a bit unconventional I just want to confirm I'm not crazy for thinking we should do a vet-sized increase instead of a protocol-sized increase.
     
  21. Peppersmom72

    Peppersmom72 Member

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    @Kris & Teasel
    Yes! You are correct. That is why I was asking if a dose increase was appropriate to do now only a few days in. She needs it. I didn't want to just do it, if it was too soon. She will get 2u this evening for her pm shot, if that's correct?
     
  22. Peppersmom72

    Peppersmom72 Member

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    My name is Missy. Pepper's appetite has been pretty good.
     
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  23. Peppersmom72

    Peppersmom72 Member

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    I'm not comfortable with the conversion. I'll stick to using the u-40 syringes. Pepper doesn't seem to mind. She's the boss. Lol
     
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  24. Kris & Teasel

    Kris & Teasel Well-Known Member

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    Just doing some thinking out loud here: increasing to 2 u tonight is doable. If you feel more comfortable going to 1.5 u tonight that's reasonable too. How do you feel about it, Missy? You've said Pepper is eating well right now.
     
  25. Peppersmom72

    Peppersmom72 Member

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    If Prozinc is safer than Novulin N then I'm ok with the increase to 2u. Her appetite seems good right now, but that can change in a blink of an eye.
     
  26. Kris & Teasel

    Kris & Teasel Well-Known Member

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    Yes, ProZinc is a gentler insulin with a slower onset in general. Try 2u tonight and get that PM dose +2 test. You'll need a little time to see her particular reactions to ProZinc. :) Do you have appetite meds on hand in case she decides she won't eat? Many people with kitties who are like this have a supply at home all the time. Would your vet agree?
     
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  27. Peppersmom72

    Peppersmom72 Member

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    @Kris & Teasel ,
    Ok. I will do the 2u tonight and do a +2 test. When does Prozinc "usually" get it's lowest? I noticed Novolin got to it's lowest around +5.

    Yes, I have appetite meds on hand that the vet gave me, if needed.
     
  28. Peppersmom72

    Peppersmom72 Member

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    Pepper hardly ever eats during the night.
    I leave food out for her, but she doesn't touch it.

    Is that going to cause a problem with Prozinc?
     
  29. Kris & Teasel

    Kris & Teasel Well-Known Member

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    No, it shouldn't. If you can, set an alarm for a mid cycle test (in the +5 to +7 range) tonight and Saturday night. That data can help you see what she does on the dose overnight. I can't leave food out either because Teasel's sister would eat it and she's on a hypoallergenic diet.
     
  30. Peppersmom72

    Peppersmom72 Member

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    @Kris & Teasel
    Is it normal for Peppers BG to go up a little at +2? She received 2u tonight.
     
  31. Djamila

    Djamila Well-Known Member

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    It doesn't look like Kris is online right now (unless she's hiding ;)). Going up at +2 isn't uncommon. BG will rise after eating, and then start falling when the insulin kicks in. Onset for Prozinc is generally around +2, so the +2 test will often (especially earlier on or when the dose isn't high enough yet) show a rise, the +3 will hopefully start to show the beginning of the drop.
     
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  32. Peppersmom72

    Peppersmom72 Member

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    Should I test again at +3 or wait until +6?
     
  33. Djamila

    Djamila Well-Known Member

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    You can wait until +6. Fingers crossed the increase brings her down a bit!
     
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  34. Peppersmom72

    Peppersmom72 Member

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    Nov 20, 2017
    276 at +6. I don't know if this was her lowest.
    How long after start of new insulin can I do a curve?
     
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