1/19/20 Zoot! AMBG=295, +3=318 +6=231 +9=258; PMPS=320 +3=236 Day 9 Ending Trial

Discussion in 'Lantus / Levemir / Biosimilars' started by Cinnie Cole, Jan 19, 2020.

  1. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    So Zoot!'s numbers continue to climb. AMBG=295 Do I continiue to not give him insulin?

    If not, when do I start insulin and at what level?

    Thanks.
     
  2. carfurby (GA)

    carfurby (GA) Well-Known Member

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    Feb 19, 2012
    I'd see if he brings his numbers down today. You could still be seeing the kibble infuence.
     
  3. Si am cat mom

    Si am cat mom Well-Known Member

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    Nov 11, 2019
    hope he comes down for you today !!!
     
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  4. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    Okay. I need to decide, though, when the numbers are going too high. He has steadily creeped up over the last week.

    He has a good appetite, but is starting to be more "urgent" about eating. He is eating a lot. I will see how it goes today with his behavior - I have not seen him drinking or peeing more. But I sense he is not a good as he was a week ago.
     
    Last edited: Jan 19, 2020
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  5. LizzieInTexas

    LizzieInTexas Well-Known Member

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    Jul 25, 2016
    Here is yesterday's condo.

    Fingers crossed Zoot!'s numbers come back down :bighug:

    Banish the kibble (and the DH?) :joyful::joyful:
     
  6. Briere Fur Mom

    Briere Fur Mom Well-Known Member

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    Sep 19, 2019
    Come on Zoot! Bring it back down. You can do it! Show mom what a big boy you are.:cat::D:D
    Have a wonderful day!
     
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  7. Tina Marie (GA) and Jan

    Tina Marie (GA) and Jan Well-Known Member

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    Jul 24, 2019
    It looks like Zoot! needs some insulin. I would give him some at PM if he isn’t down a lot by then. I would have even given some this morning.
    I’m just having a hard time believing these numbers are due to the kibble, two days later.
    Plus, with what you, Cinnie, are noticing about how Zoot! felt better a week ago, is telling.
    Still, I wouldn’t want you to take my advice over more experienced people!
    I hope I am wrong!
     
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  8. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    Exactly - I feel like it is not kibble at this point. At +3 he is up to 318. As much as I would love to hold off on insulin hs numbers are only increasing at this point.

    I feel like I need to make a decision about dosing and need help on when and how much. His last dose was 1 U, is that what I should go with?

    Who can help me decide on next steps? Thanks.
     
  9. Sienne and Gabby (GA)

    Sienne and Gabby (GA) Senior Member Moderator

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    Dec 28, 2009
    I think the kibble is out of Zoot's system. I think a try at 0.25u may be a place to start.

    If I had to guess why this happened and how to prevent it in the future, the insulin dose may need to be tapered down to a drop versus stopping at 1.0u. I think Zoot's pancreas needed the extra support.
     
  10. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    Yeah, clearly he is not producing the insulin he needs - I will test again at +6. Should I start at the normal time tonight (as opposed to right now)? Thanks for the guidance.
     
  11. Sienne and Gabby (GA)

    Sienne and Gabby (GA) Senior Member Moderator

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    I'd start tonight so you're not having to negotiate getting back on schedule.
     
  12. Bandit's Mom

    Bandit's Mom Well-Known Member

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    Oct 18, 2019
    Apologies if I am hijacking this condo, but just to understand, how would one taper the insulin dose in a case like Zoot's from 1 to zero? He suddenly went on a mission of greens without any insulin and his numbers were too low in the first few days to shoot any. In such a case, should one feed higher carb food and give insulin? I'm asking so I know what to do if I ever face a situation like this.

    Sorry to pile on to your condo, @Cinnie Cole . I was watching Zoot's numbers and siliently cheering him on..
     
  13. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    No need to be sorry at all - I have the same concerns. I would have been very hesitant to drop down by .25u increments given the situation we had with Zoot!, too. And I would never have thought to give HC/MC food and shoot - seems counter-intuitive of what we were hoping was happening; plus how could we even gauge what HC would do and what the dose should be. That would be something interesting to learn, too.

    We relied upon our Vet, who is very supportive of the expertise in this group; but it was clear giving Zoot! insulin was already dropping him into the 40s and high 30s. I don't think there was any rushing into this - it felt quite organic in process.

    Whatever the situation that caused him to start to produce his own, it did not last, but maybe next time.

    I am testing again in an hour (+6); he has been sleeping since +3, so don't expect much change. Just hoping it is not continuing to go up. C'mon, Zootie!
     
    Last edited: Jan 19, 2020
  14. Sue and Luci

    Sue and Luci Well-Known Member

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    Nov 3, 2017
    I think I'd be inclined to give a little insulin to see if you can kick start whatever was going on recently when he went all green - obviously his pancreas was working then...and it might be faltering a bit...and that kibble incident didn't help a bit as it challenged his pancreas to produce insulin and it let him down - so I'd say he needs the help, but also careful monitoring to make sure his pancreas, when it does kick in again will be able to do it's job and you'll be able to withdraw the insulin again.

    He's an interesting one though...
     
  15. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    Gosh darn it! Now he is at +5.75 = 231. (recheck right after eating 2 tbsp food was 243 so that 231 was right) And he was hungry. Well I wanted it to go down; but really - not like a rollercoaster. @Sienne and Gabby (GA) your thoughts? Should I test at +9 and delay a decision on insulin till I see a couple more numbers?

    Thanks.
     
    Last edited: Jan 19, 2020
  16. Bandit's Mom

    Bandit's Mom Well-Known Member

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    Oct 18, 2019
    The only thing I have managed to figure out about feline diabetes is that it is one roller coaster! It is a "box of chocolates"!!!
     
  17. Tina Marie (GA) and Jan

    Tina Marie (GA) and Jan Well-Known Member

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    Jul 24, 2019
    Oh no . . . look how hard he is trying! It's a good thing.
    I agree that Zoot! was having so many greens after coming off that last 1 unit dose, it would have felt wrong to give him any insulin. It looked like he was having some spontaneous, rushed remission!
     
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  18. Sienne and Gabby (GA)

    Sienne and Gabby (GA) Senior Member Moderator

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    Dec 28, 2009
    If it were me, if numbers were not in normal range at PMPS, I'd start insulin (or wait until AMPS at the very latest with the came caveat).

    The idea isn't to jump to HC/MC when bumping up the carbs unless you're already feeding Zoot a food that's in the 8% (give or take) range. You can still use LC food just food that's at the upper end of the LC range.

    Also, there are a couple of ways to micro-dose. One way is to count the number of drops in 1.0u or 0.5u and use that as a means of adjusting the dose. As an example, if there are 10 drops of insulin in 0.5u, 0.1u would be 2 drop so you would eliminate 8 drops of insulin. A "drop" of insulin (i.e., <0.1u) would literally be one drop (eliminate 9 drops). Alternatively, when you need to shoot less than 0.1u, push hard on the plunger, insert the syringe into the insulin container and then release the pressure on the plunger. There will be about 1 drop in the syringe.

    @Bandit's Mom (see above)
     
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  19. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    Thanks - I don't want to switch foods now. His evening food LC has 4%. As for the insulin, I will maybe try the drops method, but I don't know if I can see count accurately enough. Will practice now. Thanks.
     
  20. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    So he was 320 at PMPS, and I am giving him .25 unit Lantus. Will check at +3 to see if it helps at all.
     
  21. Crista & Ming

    Crista & Ming Well-Known Member

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    Jun 10, 2018
    Darn :( Sorry about the trial ending. On the bright side, you get to spend more time with us! (LOL I'm kidding. Trying to make lemonade out of lemons.)
     
  22. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    I can live with that! I hope the .25 unit of lantus tonight has some effect.
     
  23. Sienne and Gabby (GA)

    Sienne and Gabby (GA) Senior Member Moderator

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    Dec 28, 2009
    Remember, there's no depot. It will take a few days to get the depot reestablished.
     
  24. Bandit's Mom

    Bandit's Mom Well-Known Member

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    Oct 18, 2019
    Hopefully his pancreas just need a reminder. Fingers crossed.
     
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  25. Cinnie Cole

    Cinnie Cole Member

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    Jun 1, 2019
    @Sienne and Gabby (GA) @Bandit's Mom So that little amount may have done some good - at +3 he is 236 and he looks perky and is a bit more active and his fur looks better. So I will hope that his pancreas just needed a reminder of its job.
     
    Last edited: Jan 19, 2020

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