Constipation, too much combo Lact/Mira, the runs/vomit. Bupe 2nite?

Nelli was having such a great day… I over did it I think on the lactulose and Miralax Not individually but 3 mg (RX 2 to 3 mL) and about 3/4 of a tablespoon Miralax all within about 5 hours today
I believe this is what brought on the “runs” , subsequent moaning/yell, leaves litter box to vomit foam

I am a bit suspicious Bupe may be causing the constipation but not ready to take her off yet... am going to try a regimen of SEB, aloe and pumpkin- waiting for Smooth BM Gold to come in and start

Nelli quality of life is noticeably better with Bupe (every 2-3 days) and Adequin. every four.
My question... today is due day three for Bupe, (15U subQ). Would you give it to her?
Thanks for your opinion I greatly appreciate it!!!