Tubby is 18 and has been on insulin for a couple of years. Original vet just did FBG and fructosamine tests and had Tubby on 5 units of ProZinc and Purina DM, new vet insisted on the 12-hour curve. I resisted but after some random elimination incidents I bit the bullet, got the glucometer, and learned how to do it. The result: two curves and this boy may be in remission. I'm still testing twice a day and I know this may not last, but wow what a difference! Tubby is much more active and alert. If you are new to diabetes and reluctant to get into the testing, DO IT. For yourself AND the cat! Geez when I think of what I may have been doing to this wonderful boy (AND the money I spent on insulin and syringes)...I'm like the Claus von Bulow of cat owners. Thank goodness Tubby's bloodwork is excellent so no evident damage to his innards. I've been lurking for several weeks and I appreciate all the great info.