Hi my name is Jim and my cat Ripley was diagnosed with diabetes about a month ago. The vet put her on 1 unit (u40 needle) twice a day. At the time she was also on prednisone which wasn't helpful. The vet couldn't do a glucose curve so I just checked her levels using a reli on human meter. The vet did manage to take one reading using their meter and the reli on meter. They said to add 50 to my readings to normalize the readings. I changed to u100 needles and gave her 3 units, twice a day. She still lost weight and pees a lot. I ran a BG curve today starting around 0700 and tested every two hours the last being at 1500. Her readings were (normalized by adding 50) 442-412-396-394-393. So essentially no change. I'm going to up her dose tonight and was wondering if I should up to to 4 or 5 (u100 Needle). I also was wondering if I should give her the shot one hour early. Thank you for your help. I'm going crazy and the vet isn't helpful at all. Jim. Oh I did test for ketons and it read as trace.