My Beloved Boy Wylee was diagnosed last April. He is 6 years old & the drinking & Urinating was very out of control. I am a vet assistant & felt I picked up on it rather quickly. He is a sweet boy but DOES NOT tolerate his vet visits at all. The first Dr. I work with put him on Glipizide 2X daily- This did nothing. Then he put him on Humulin U100 Insulin - just one unit in the AM & one in the PM. Took him in to work for Fructosamine test & he is at about 700- I tried a different Dr. at work & we increased his dose on the U100 several times- more Fructosamine tests- no change. The last change has been to change him to P roZinc U40 Insulin. Yet ANOTHER Fructosamine test - again bad results. I am now at 4 units in the AM & 3 in the PM. No clinical changes. I am feeling very defeated & do not know what to do. The Doctors have sadly not been much help. I have read that there has been success in mixing both a short & long acting insulin. If anyone has any comments & has been through this- I beg you to please share. Thank you!