I would appreciate any/all advice, help, and input you can give... Back story (sorry it's a long one): A year ago, I found an abandoned black cat across the street from my house. She was skinny and chatty and friendly. I took her home, fed her, and started looking for her family that had to be super worried about her whereabouts. A few weeks went by and no one claimed the stray cat, so I named her Remi, got her microchipped, and vaccinated (she is approximately 4 years old now). In the midst of all of that, I said a tearful goodbye to my sweet diabetic Shasta. All was going well with Remi, except I noticed that she would growl at the horses in the pasture next door, as well as my little outside feral, Mamacita. I figured that she suffered from PTSD from being dumped outside and fending for herself. Fast forward to May: while helping friends care for an abandoned litter of kittens...I fell in love. I ended up bringing 2 of the kittens home...Linus & Lucy. They've been living in my spare bedroom ever since I brought them home...they are approximately 8 months old now. I knew that introducing Remi to the kittens would take time and lots of energy, but now I'm starting to wonder if this can ever happen. I've tried several techniques to introduce them...the baby gate with towel over it...feeding them on either side of gate...nothing has worked. I bought the Feliway Pheromone Diffusers and that seems to have calmed Remi a bit, but not enough...she will still charge the baby gate, hissing and growling. Also, she gets a Zylkene capsule once a day...seems to help, but again, not enough. This past Monday night, my feral cat and either a neighborhood cat or raccoon got into a fight outside my kitchen window. Remi (strictly indoor cat) looked like she stuck her tail in an electrical socket...poofied her whole body. She was crouched, ears back and growling. I ran out to break it up (ended as I ran out...neither animal to be found...Mamacita turned up about 10 minutes later). I have no idea the kittens reaction to the noise as it took me a while to get to them. Since Monday, Remi has lunged at me once in an aggressive manner and bitten my hand once when I picked her up. The kittens have been different, too...but I think it's due to the diffuser running out of juice. When the diffuser is working well, Linus is chill and a bit standoffish but he doesn't run from me and Lucy is the most amazing snuggle bunny like she was when I first met her. When it runs out, Linus become the snuggle bunny and Lucy is standoffish and afraid of me. This freaks me out so much. I understand how diffusers/pheromones work, but here is my concern w/ regards to diffusers: I fear that it has truly altered Lucy's state of mind. Before I plugged in the first diffuser, she was a happy-go-lucky kitten and now, without the diffuser, she fears everything...noises outside the bedroom, she fears me, etc. I put in a new diffuser last night and this morning she loved on me and by this afternoon, she cuddled me so much I was dying of heat because she wanted to lay on my chest! I do not know what to do...put the diffuser back in keep buying more and more and be happy that Lucy is wanting snuggles, but knowing that if it runs out...she'll fear me?!?!?!?!?! Or leave it out and see if I can't win her over with love and kindness and treats?!?!?!?! Kitty prozac: Linus & Lucy have an appointment with the vet on Friday to get microchipped. At that time, I will ask him to prescribe Remi a kitty prozac/anti-anxiety med. Before going there, I would love anyone's input with regards to these meds. Are there any anti-anxiety meds that I should refuse due to long term health problems? Side effects? Are some meds better than others? HELP! Any other help or advice is truly appreciated. Ultimately, I'm worried that I will never be able to integrate the kittens with Remi. I have feared that she will try to kill them. When my sweet feral kitty comes and sits outside my kitchen window, Remi goes at her (via the window) like a ton of bricks. I'm beginning to think her mental state might be why she was dumped. Thank you, in advance.