My kitty has been in the 500-600s for weeks now. She started on NPH and went from 1 to 2 to 4 to 5 units twice a day. When 5u still wasn't affecting her numbers, I requested an insulin change and we went with Vetsulin. Her first curve on Vetsulin was 2u and it was even higher than the NPH results, she went home on 3u and there was no change. Still ravenous, etc. The vet did another curve a week later at 5u and she dipped all the way down to 73. The vet sent her home on Monday at 4u on Vetsulin. The next morning we could see an IMMEDIATE difference. Prior to this she was ravenous and easily eating 2 cans of Fancy Feast per meal, with snacks in between. However after the dose change to 4 she has gone almost completely back to normal in attitude and appetite. The problem is, she doesn't have a very big appetite normally! She has never been the kind of cat to finish a meal, she's just not a big eater. Tonight she didn't even eat enough for her shot. She ate maybe a fourth of a can of FF and maybe half an egg yolk after much prompting. After about an hour or so of trying to get her to eat even more, I gave her 2 units. I hope that was okay, she did eat a normal amount for herself pre-diabetes, but it just doesn't feel like enough for 4 units. The other problem is she is only 4 lbs! Prior to diagnosis she was more of an 8 lb cat, diagnosed at 5 lbs, and over the past couple months is down to 4.1 despite her large appetite until recently. I'm just so afraid to give her such a big dose when she's so tiny and not hungry, but until a few days ago we just couldn't get her glucose levels down. Does anyone have any advice? I am calling the vet in the morning of course.