Morning all! I would really like some assistance trying to decode my buddy Lou's spreadsheet. We had been having some success (if you can call it that) with slowly increasing his dose. I suspected he needed to be on 2.0 units, and so I was pretty excited when we got to that point. Things started out promising enough, but this last week I feel like things have gone off the rails. There are times it seems like the dose is working exactly how I want it to and the next preshot numbers reflect that, but then I randomly have these angry hot pinks and reds. They're dismaying because he hasn't gone into the 400s since his diagnosis. I've had a couple of times where the insulin is not working at all (see last night), and then this morning he's in the 400s. I have been extra vigilant and I have not had any fur shots. What's even more depressing is he reached a normal BG yesterday and we were so bloody happy for a normal cycle... but that nadir happened at +8. There was a late nadir (+7) a while ago, but since he's had earlier nadirs that I can see. This late nadir throws me, because then it affects his next preshot BG. Long story short, I am at a loss as to what's going on, so I figured I'd post to see if anyone else can see something I'm missing. I decided to post in the Main Health forum to get more eyes. It's his 4 month FD anniversary today, and I find myself rather depressed with his progress. Definitely not where I thought we would be at this point. I appreciate any insight you can give me!