I've posted this on the Lantus forum, but in case someone new sees it: I gave Malika a week break of shots moving from Vetsulin to Lantus. 1st shot this morning of .5U took her from 380 to 264 at 8:00 am. It's time for her second shot, I tested at 7:00 pm and she's at 91. I'm hesitant to give her more in an hour. Suggestions appreciated. I have her a treat about 2 hours ago - Orijen - which she threw up with a hairball about 3 minutes later.