Dosing Help - switching to ProZinc w/ U100 & High Dose Cat

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taffysmom

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Hello again :) Tonight I am supposed to switch Taffy over to ProZinc but after calling 5 pharmacies - no one had U40 syringes. I have plenty of U100 ones. I printed off the conversion chart so I think I'm good on that front. I ordered U40 but the online pharmacy has to confirm Rx and who knows how long that will take.
Here's the problem. Last week while at the vet I was told to start her off at 3 units of Prozinc. According to the chart that would be 7.5 of Lantus equivalent which is what her next bump is up to.
On the label it says 5.5 for Prozinc which would be double the dosage I've been giving her for Lantus correct? I called the vet office to ask and didn't get a call back. Good thing I couldn't find the U40 and I just received the ProZinc from the vet today so I have not used it yet.

And just to add a nice spin on things Taffy developed bad diarrhea on Saturday and then started vomiting on Sunday - within an hour of eating anything it came right back up one end or the other.
Got meds from vet this morning and thankfully the vomiting has stopped. The poo is still runny but not watery anymore. This cat never lost her appetite or her attitude. Guess I can be grateful for that but I was up all night cleaning puke and poo and checking on her. And I think it was the liver in the chicken and liver pate that got this all started. I vaguely remember her having an intolerance to liver of course after she scarfed it all down.

I've been feeding her small amounts every couple of hours so not to completely warp her system since it seems to be back up and running on the front end.
So since she was sick last night I lowered her dose on Lantus from 7 to 5. Because she was puking all night but still eating I gave her 3 units of Lantus this morning.
Now that she's eating and not puking I'm not sure if I should do 1 more Lantus dose at 7 or make the switch to 3 units of Prozinc or maybe give lower doses and work my way back up.

and b/c I know I will get asked...no ketones..no pain..no dehydration..no loss of energy(surprisingly)..no I haven't tested for acro yet...lantus doesn't sting - I just wanted to try a different based insulin ;-)
Thanks!!
 
Re: Dosing Help - switching to ProZinc w/ U100 & High Dose C

I can't give you any advice, I have never used ProZinc. However, I added a post on the PZI group to let them know you need some help.
 
Re: Dosing Help - switching to ProZinc w/ U100 & High Dose C

I am not sure. Although I have helped a lot of people with ProZinc, few people switch from Lantus. And her being a high dose kitty complicates things. The issue is the shed that Lantus has and that it may last longer than 12 hours - you don't want to throw another dose of insulin when the Lantus is still working.

I guess I'd consider lowering the dose by half (?), monitoring carefully for bg levels and ketones for 2 cycles and then increasing every few cycles by .5 until she is in safe ranges.

Yes, 3 units of ProZinc on a U100 needles would be 7.5. You are using this chart, right?

http://www.felinediabetes.com/insulin-conversions.htm

What dose of Lantus is she on now?
 
Re: Dosing Help - switching to ProZinc w/ U100 & High Dose C

For the last week I've been giving her 7. due to her being sick I droppedit to 5 last night and 3 this morning. she just tested at 410 and she has had plenty to eat so I gave her 7 units of lantus. will do the switchin the morning after I have gotten some sleep. and watch her better. sorry for the typos...sending from my phone
 
Re: Dosing Help - switching to ProZinc w/ U100 & High Dose C

When using a U-100 syringe with a U-40 insulin, always report the actual units of insulin, not the syringe marks.

Because ProZinc has only 40 units per mL, the volume you need to give will be much larger than the volume (not units) of Lantus.

Also, the formula for conversion is U-100 mark * 0.4 = ProZinc dose. You've got the chart already, but if you misplace it, you'll be able to recreate it when needed.
 
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