There are some Traditional Chinese Medicine herbal formulas for Hyper-T, but you would need to see a holistic vet in order to get the best diagnosis for them. However, I do believe that most TCM and homeopathic treatments for Hyper-T are meant for situations which the Hyper-T is mild, which does not sound like this case as there has already been respiratory and heart involvement.
The transdermal Tapazole gel would be a solution if your kitty is having problems with the oral form, although the meds in both forms would have the potential to cause the leukopenia (low white cell counts). Some cats with untreated Hyper-T also can develop a similar complication. Was the CBC done before the Tapazole was started normal?
Please don't rule out the I-131 treatment just because your kitty is 16. I had Sasha treated with the I-131 last year at age 16 and she has done wonderfully since, even despite other diseases. If your kitty is not tolerating the Tapazole, for whatever reason, the I-131 may be the best choice.
Hyper-T does also have the potential to increase BGs and cause insulin resistance, so treating the diabetes at this point is even more critical since the BGs are most likely also being impacted by the Hyper-T.
ETA: You may also want to check out the Yahoo Feline Hyper-T group. It is a great resource: [
pets.groups.yahoo.com]
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Sasha's Labs