Hello there, We're living together with a soon-to-be 14 yo diabetic Siberian, who's recently has lost his regulation. Vet suggests higher insuline doses, I'm concerned about cat's pre-shot levels. Read on for details. Muta has been diagnosed with diabetes ~2y ago. We knew it'd happen at some point, as his pancrea is underdeveloped, and he has had related problems as a result (exocrine pancreatic insufficiency, enzyme supplementation for the food). Once diagnosed, we had problems getting his levels stable; we succeed after switching his diet to wet food only (4 pouches of Royal Canin Diabetic per day). He'd still try to steal dry food from two other cats in the household. His "stable" situation was around August last year: 1.5u Prozinc every 12h 2 pouches of Royal Canin Diabetic every 12h pre-shot morning average levels of ~10mmol/L "sensible fructosamine levels" (don't have an actual value here, vet's wording On the way there we've changed the diet couple of time, scored a couple of mild hypo episodes (primarily disorientation, no severe symptoms). Forward to last month. He destabilised *slowly* over time since ~February or so, to arrive at situations where he'd routinely get >25mmol/L blood sugar levels pre-morning shot. The blood test results were seemingly normal, not indicative of any infection that might have contributed. The fructosamine levels were off the chart, which prompted vet to suggest an insuline dose increase. We've increased the dosage to 2.0u, and things improved a bit. Problem is, the pre-shot levels are still fluctuating, sometimes reaching 20 and above. The average hoovers around 11, but there doesn't seem to be a solid baseline. For example, here is a week worth of measurements, mid May (two measurements, morning and evening pre-shot): Monday: 8.9 - 7.8 Tuesday: 5.9 - 8.7 Wednesday: 16.1 - 5.9 Thursday: 15.8 - 5.2 Friday: 14.3 - 5.2 Saturday: 6.2 - 7.6 Sunday: 4.3 - 25 The vet ran a curve, and wasn't happy with the result (pre-shot: 8.7 - 9.3 - 20 - 20.4 - 14.1 - 11.9). They've suggested further dosage increase, up to 2.5. Which makes sense in the light of high values through the day, but the lows are worrying. I'm unsure what causes those. The highs, I'm suspecting it's the dry food he steals from the other cats, every now and then. As you can expect, there's plenty more medical history to narrate here, but the primary problem I have right now is reconciling the narrative from the vet, who seem to be OK with the low pre-shot results and my own anxiety about hypo episodes. I'm still waiting for the results of fructosamine test done after 3weeks of 2.0 dosage. I don't have any way of providing monitoring through the day, and I'm really anxious about the cat hitting a hypo when there's noone around to help. I have historical records of his blood sugar levels, primarily on paper though, so I can dig up data on demand Opinions and ideas most welcome!