6/20 Jack 281 @AMPS, increased to 6.5

Nice solid yellows that first day at 6.5 units. Paws crossed he trades them in for some blues soon. That 217 looked promising. I think that's his lowest yet?

I've been meaning to mention something to you. It looks to me like there is something causing insulin resistance in Jack that is causing him to need a higher dose than average. We suggest to people when they get to 6.0 units that they consider getting their cat tested for a couple of secondary endocrine conditions, specifically acromegaly and IAA (insulin auto antibodies). My girl Neko had both. Acromegaly is caused by a benign growth on the pituitary that causes excess growth hormone to be output, which in turn causes the diabetes. Approximately 1 in 4 diabetic cats has it. IAA is a separate condition caused by antibodies, which are sort of like the body's allergic reaction to injected insulin. The antibodies trap the insulin, preventing it from entering the cells. The testing is a blood test, that is sent to Michigan State University. The reason for mentioning it is that if Jack were to have one or other of the condition, there are some things to watch out for. And there is treatment for acromegaly. Not all cats with these conditions get to higher doses, but if you get to higher doses with a low carb diet, there's a good chance there's an underlying condition.
 
Wendy&Neko said:
Nice solid yellows that first day at 6.5 units. Paws crossed he trades them in for some blues soon. That 217 looked promising. I think that's his lowest yet?

I've been meaning to mention something to you. It looks to me like there is something causing insulin resistance in Jack that is causing him to need a higher dose than average. We suggest to people when they get to 6.0 units that they consider getting their cat tested for a couple of secondary endocrine conditions, specifically acromegaly and IAA (insulin auto antibodies). My girl Neko had both. Acromegaly is caused by a benign growth on the pituitary that causes excess growth hormone to be output, which in turn causes the diabetes. Approximately 1 in 4 diabetic cats has it. IAA is a separate condition caused by antibodies, which are sort of like the body's allergic reaction to injected insulin. The antibodies trap the insulin, preventing it from entering the cells. The testing is a blood test, that is sent to Michigan State University. The reason for mentioning it is that if Jack were to have one or other of the condition, there are some things to watch out for. And there is treatment for acromegaly. Not all cats with these conditions get to higher doses, but if you get to higher doses with a low carb diet, there's a good chance there's an underlying condition.
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I was going to ask what a 'high' dose for Lantus/Semglee was, since he seems to be constantly increasing doses. I will send a note to the vet to ask about these blood tests; thanks so much for posting this. He still refuses to eat the wet food, once I get my loan secured and septic fixed I will try again with full force to get him onto wet food. And yes, 217 was the lowest yet!
 
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