Hi, I read something in a post, then did a search and came across this posted by @Sienne and Gabby (GA): “You don't rub the injection site because once Lantus is injected, it forms microcrystals that are deposited in the fat tissue. These crystals dissolve over the course of the cycle which is in part, what gives Lantus its duration. Not all of the crystals completely dissolve in one cycle and this is how the depot forms. If you rub the shot site, you break. up the crystals.” I have been rubbing the injection site after each injection, thinking it would make the shot sting less I feel so stupid, I now think that maybe doing this has been the reason it’s been so hard to get Scout’s numbers down - a BIG contributing factor at least. Could this be why it’s been so hard to get him regulated? I am kicking myself to have missed this There are no words to explain how bad I feel right now.