Hi all - I'm fairly new to the board, and started glucose monitoring at home just two weeks ago. I've had a terrible year so far (deaths in the family, health concerns, etc. etc.) but nothing is stressing me out more than trying to get my diabetic cat Rocket regulated. He was diagnosed early Feb., and his vet started him off at 1.5U of Prozinc every 12 hrs. He had an infection at the time, his glucose was over 450 at the office, and was not eating, so he was hospitalized for two days. Anyway back then I knew nothing really about feline diabetes... long story short, his numbers are not getting better, and his vet has slowly been increasing his dose. He's currently at 4U every 12 hrs, but his numbers are terrifying to me. I'm almost embarrassed to have anyone else see his spreadsheet, but I'm at a loss. My heart sinks every time I take his levels. He's on a strict (low carb) wet food only diet, and has been since the second week of February. Obviously I'm concerned about something like insulin resistance and/or acromegaly, but he doesn't have any outward signs of it and his vet doesn't seem to think that's a possibility (I do realize it can be underdiagnosed). Thankfully we have an appt. on Tuesday for a second opinion with another vet who supposedly has a lot of experience with diabetes, so I'm hoping to get some more ideas/advice/guidance. Thank you if you've read this far. I guess my main concern is, what damage are these numbers doing to Rocket right now? I'm so worried. Actually in the last few days (since our last dosage increase) his water intake seems less, and his litterbox isn't as much of a warzone, but his numbers won't budge. He still eats, and hasn't lost weight really since Feb. (hasn't gained, either). Our appointment Tuesday can't come soon enough. Any ideas or advice from any of you who have gone through a similar situation? I love this cat to pieces, and I appreciate any input more than you all know. Big hugs to all of you.