Duke is a tortie, Maine Coon mix. He was diagnosed shortly before valentines day this year. He has always been fed a low carb diet - wet Friskies for most of his life. No dry food except a little as a treat. We just started home testing. He started on Vetsalin. He is currently taking PZI compounded by a local compounding pharmacy. It is U-100. Last week he just crashed. (please see diabetes heath forum introducing Duke post for details). He was on 3 iu 2x. We were later advised to go to 2 iu which we did. I just started a spreadsheet. My current concern is that Duke tested last night near 500 so we gave him 3 at 7:00 am. Tonight at 7:00 about an hour after eating: PMP 212 I didn't know if we should give him a shot or not. I went ahead and gave him 2 iu. I will test in the AM and watch him tonight. I was unsure if I should give him a shot or not. Should we have a no shot value at this time? I know we don't have much data yet. This has been especially emotionally draining on my wife. Duke is a momma's boy. Being a scientist by training, I can take a more detached clinical approach. This has caused some tension. I will do a curve this weekend.