Panter didn't show up for his morning shot yesterday. He had eaten his nightfood though, at around 2-3. So up to this time everything is normal. Found him under the bed later on around 18-19, not in good shape. Don't know how long he has been there. But strangely his BS was 21.2 (+12) - like his 'normal'... He didn't want to eat or drink, just laying still. I made him a litterbox, but he didn't want to use it. He wanted to go out several times. In the end -in the middle of the night, I had to follow him out, and he disappeared in the dark...hasn't returned... and I'm soo worried... The strange thing is that I kind of thought we were on the right track with this new insulin - he is still high, but it has started to work, he is down in yellow, sometimes blue area on nadir. And he is - was - in good shape, hunting, playing, purring, friendly, very normal. I'm afraid it is something else. Organs failing or something... Any thoughts? Best regards, Gøril.