I posted in the main forum, but didn't get any answers… So I went ahead and posted my question on the Facebook page. Now I think I'm really really sorry… This morning Wynken acted like he had a urinary tract blockage. I thought this was really odd, since he had had a urethrostomy about six years ago. He has not had any urinary troubles since the surgery. ( he used to block all the time ) One of the reasons I knew something was really wrong was he did not allow me to get his AMPS, this morning. He's been good 99% of the time.... He kept jumping down off the bench where a test him and going in the litter box. I wasn't sure if this had to do with me dosing him with pro fender yesterday... Wasn't sure... BUT He was eating well, so I gave insulin. I ran home at lunch to check on him, fully committed to taking him to the vet if I thought he was blocked. Even though he was resting comfortably (BG of 421!) I found only little teeny tiny Pee balls in the litter box. So I called and they recommended bringing him in. He got a really good examination including an ultrasound. He was not blocked, but they were able to get some urine (cysto) and analyze it at their internal lab. There was blood present and white blood cells, so the vet recommended and gave a Convenia injection. My main question tonight was whether it was safe to give him D mannose powder on his food which I had learned was good for urinary tract issues some months ago. Although this question was basically answered (it's safe)... I got a lot of very negative information about allowing him to get Convenia. Now I am sad and scared - and I feel stupid for not knowing enough to ask that a culture and sensitivity test be run. Thoughts?