http://www.felinediabetes.com/FDMB/threads/5-13-asia-amps-171-aha-an-important-observation.195515/ Asia is doing really well. There is one thing I gained from the vet visit fail on Saturday is that she needed and can have more pain meds than I was giving her. Currently she is getting 1.5mL bupe every 7 hours. I tried for every 8 and it was too long, every 6 was too close, so 7 it is. We are about past post vet freak out numbers and hopefully that combined with no pain might bring her numbers back down a bit. She is not in pain and that makes me happy. She spent a good amount of time playing with her bird toy last night and even chub run chased it down the hall a bit. Have to run out for several appointments this morning so hopefully she behaves. PSA for the day on Cerenia: So I noticed a trend on here that some people weren’t having much luck with Cerenia and ondansetron was being suggested as working better/working differently/used in conjunction with Cerenia to provide nausea relief. No doubt some cats respond better to one than the other or perhaps even need both, but I found some interesting info on how Cerenia is dosed and wanted to make it available because Cerenia works for 24 hours and ondansetron needs to be given multiple times a day. Which only means if Cerenia can work for your cat, it last a lot longer and is probably less expensive for needing to be given less frequently. The first time Asia got Cerenia was at the vet’s office and it was an injection. It was a miracle for her, she wasn’t eating well and it was a game changer. I was sent home with a compounded liquid form. When the shot wore off and I gave the oral version, it did absolutely nothing. Asia stopped eating again. I wish I still had the bottle to see what the mg/mL was, but I threw it out long ago. I’ve been giving the sub-q injectable version ever since and we are both happier about that! I came across some (outdated) info that Cerenia (maropitant) should be dosed 1mg/kg period. That info is still out there and likely some vets still unknowingly prescribe 1mg/kg regardless of oral or sub-q delivery. Then I found some info on the Merck Veterinary Manual and Plumb’s (like the PDR for veterinary drugs) and they both say the oral dose (PO) is essentially double the sub-q (SC) one. Thought that could explain (for some cases) why Cerenia wasn’t working for some cats. From Plumb’s: From Merck Veterinary Manual: Even the Merck info seems to already be out of date as a cat dose had not yet been established and it doesn’t seem to be half the dose as is for dogs, but instead based on weight and growth stage/age. And Merck still lists 5 days as the maximum length of time for use. But they acknowledge the dosing is different depending on method of delivery. So if you think Cerenia just doesn’t work for your cat, check your prescription bottle for the pill form and if it isn’t 2mg/kg or very close to, it likely isn’t a therapeutic dose for your cat and maybe have a discussion with your vet about it too so you can make the next cat’s life easier.