Hey all, Just started my man up on ProZinc. So far he's getting 2u twice daily. His numbers have so far been pretty high, and I'm fairly positive he'll need to up the dose. I would like to get his numbers down ASAP - partially because he just had a scary episode of DKA and I do not want to see it happen again. Our previous vet had us go very slow with Lantus (having us hold him at a dose for nearly a month before even taking a proper curve/adjusting) and I want to avoid this scenario with our new vet. The advice on this forum seems much more well-researched and logical than most of the vets I've worked with so far. That said, I would still like to keep our doc in the loop and proceed with their consent for all changes. From what I've read on here, the effects of ProZinc should be noticeable after 3 full cycles/36hrs as opposed to nearly a week for Lantus. Here's a few questions: Does this mean a curve of the 4th cycle should be accurate? Are there any other considerations? Since he's just now switching to ProZinc, is there a longer waiting period? The sticky mentions there's no official protocol for ProZinc, but are there any studies at all to reference that advocate for 3-cycle changes? Where does this number come from? Asking partly for my own peace of mind, but mainly to show to the vet in case they ask for unnecessarily slow dose changes. Thanks!