Hello. My cat is Sammy. He is a mix between a Tabby and a Siamese, which makes a beautiful grey striped tiger look. Sammy is 6 years old. History We started Sammy out on Vetsulin. He stabilized at 7 units. But unbeknownst to me he was showing the early warning signs of Pancreatitis. He stopped eating his wet food and was only licking away the gravy. This was going on for months. At some point I decided to switch Sammy to a less expensive insulin. I switched him to Novelin, the long lasting type, N I think. Sammy had a Pancreatitis attack and was hospitalized for three days while he got intravenous Novelin and Water. His Ketones were very high. His pancreas recovered fast while he was on intravenous Novelin R. They put him on Antibiotics and on Antacid's and something else to help with nausea. These were all short term prescriptions. Sammy had lost weight and was about 9 pounds We brought Sammy home on Novelin N at 3 units and took him back in about every 3 days to measure his insulin. They uped his dose one unit each visit because he was running between 300 to 500, normally in the 400's. When we got Sammy up to Novelin N 10 units, he still ran in about the 400's. But Sammy was gaining weight and got back to 10 pounds. I believe Sammy is best when he is at 11 pounds. For food we feed him a measured amount of Science Diet WD Last week we did a Glucose Curve. Sammy responded to the insulin within the first 30 mins with a dip but in a short time after that he spiked back up and stayed high. Since we were not getting results on Novelin we switched back to Vetsulin. They had me start at 6 units. Now we are all the way back up to 9 units. Still Sammy is still running in the 400's. We are using the U-100 syringes so we do the 2.5 conversion in order to get the right dose amount. Today we did a Frutosamine test, it was high and did not seem to give the vet any ideas on what to do next. He is a indoor and outdoor cat. We ended up finding out he was sneaking the neighbors food at night, so we do not let him out at night. If Sammy is throwing up I would not know, he hides it from me. The good thing is Sammy is not acting like he is starving any more. His water and urine are high, but not extreme. He is gaining weight, he has a good apatite and eats all his food eagerly. But the bad thing is he is not responding to insulin he runs in the mid 400's. I would love ideas from you on what you suggest we do next. I have a human glucose meter at home. I have tested his blood at home, mainly to see if he is high or low. Thank you for your insights!!!