Mollycat Hi, I'm a new member. I have a 12 yr old male cat . Diagnosed 11 mos ago and still not regulated. We started on Lantus in April 2018. Blood sugars averaging around 400, never less than high 200's but right back up to 600's so we kept increasing by half units. . Eventually up to 7units twice a day, vet suspecting insulin resistance. We recently switched to Prozinc this Feb 15 . Started at 1 unit for a week. He was awful...drinking almost constantly, flooding the litterbox and eating an unbelieveable amount of food. The blood sugars off the meter over 600. Up to 2 for a few days, 500 plus, up to 3 few days, still high, 4, then, 5 now 6.This past Wednesday the am test was 286. I was told he is insulin resistant and keep him at 6. Two hours later it was almost 500. Today's test before food or insulin was plus 600. He's lost weight but not drinking a lot or flooding the litter box. Eating only friskies pate and fancy feast classic pate. No dry. In daily contact with vet. They feel at this point just watch for clinical signs and test at various times throughout the day. I'm a registered nurse and and using the Relion glucometer , testing on his ear without difficulty. Acromegaly had been mentioned as a factor. He does have irritable bowel but no vomiting or diarrhea. I read these forums and appreciate any input. Thank you!!