Re: 2/5 Jan and Buddy AMPS 110(late) +1 101 +1.15min 91 +1.5 85
Question: I think Buddy's number for IAA was a 72, so lets say thats high, so does that mean that a number of 45 mean its less problematic or a number is a number?? Don't know if that sounded right??
I don't know right off what the normal ranges for cats IAA are, but The IAA test is used in humans as well. It can be used for several reasons. It can be used to diagnose early Typ I DM or determine if a child with a gentic family predisposition is likely to develop IDDM. It can be used to "catch" someone who is having bouts of hypoglycemia and the doctor suspects that they are cousing it themselves by injecting insulin. (Everyone will develop some antibodys to injected insulin) so if the level is more than minimal it means the peopson has been exposed to injected insulin and has likely caused the hypoglycemia episodes themself. It can also be used to evaluate a suspected insulin resistance (this is what Buddy is showing) I don't know that the level is closely related to how much resistance there is, because these levels can rise and fall in repsonse to the amount of insulin given etc. For most antibody tests there is a only a minimum level and anything above that is considered positive.
Let's say the minimum is 10 (everyone who recieves insulin will have some antibodies but usually less than 10)
Over 10 is considered positive for insulin resistance
Is a person who has a level 12 at the time of the test less resisant than someone who has 50? maybe.....but a that test is only 1 number at one second in time and is influenced by alot of factors. So it could be that 2 hours later Patient A is at 35 and Patient B is down to 15. But at levels above 10 a person would be considered IAA positive and most will always have numbers above 10 or higher as long as they remain positve.
One of my Antibodies doesn't relate to the disaease activity. It is solely for diagnotic purposes. It is given as a proprtion
ANA is found in all persons at a level of less than 1:40 (this means negative and the disease Lupus is highly unlikely)
a level of 1:80 is considered a positive result but unsupportive of a Lupus Dx (patients with other autoimmune diseases or a relative with Lupus or persons over age 65 often have levels this high)
a level of 1:160 is consistant with an autoimmune disease Lupus is possible but not definate
1 level of greater than 1:320 is supportive of a Lupus Dx when other symptoms and tests support the Dx (levels this high are rarely seen in persons without Lupus)
I have often had levels >1:1280 (thats 5 times the normal limit) and I was symptom free and feeling great, other times at levels in the 1:320 range I was quite sick. But since having this disease I have never been below the 3x normal range.
Other antibodoes do seem to coorelate with activity and can be used to determine if a persons symptoms are caused by a disease flare or something else like an infection etc. Higher levels mean more disease activity.
For the most part these AB test are purely diagnostic and not practical for making Tx dicisions.