? 3/23 Sir Thomas AMPS 7.8

Sir thomas vet notes update/ summarized:

Emergency Discharge Summary
Sir Thomas presented to us for evaluation (Note: I brought him in with reported 3.8 BG and administered honey). He had previously been diagnosed with diabetes. All along he has not been eating well. He has been becoming hypoglycemic, even with decreasing doses of insulin. SIr Thomas's vital parameters were within normal limits. On physical examination, we found that he appeared slightly dehydrated.

Diagnostic test results:
1. Bloodwork:
1. Liver values were mildly elevated (improved compared to regular vet bloodwork)
2. the blood sugar level was high on presentation but became more normal during his stay. We suspect that he had a high blood glucose initially due to stress. His previous high blood glucose and high serum fructosamine were suggestive of diabetes melitus. This change/improvement in his ability to regulate his blood sugar suggests that he either went into diabetic remission quickly and/or was 'pre-diabetic'

2. Urinalysis
1. Some glucose and struvite crystals
3. Abdominal Ultrasound:
Conclusions:
1. mild hyperechoic mesentery surrounding the kidneys. Differentials include an acute kidney injury from a toxin vs a inflammatory glomerular or interstitial nephritis vs less likely a pyelonephritis. It is unlikely that this is a normal finding for this patient.
2. Multiple chronic renal infarcts, left kidney
3. Diffusely, homogeneously hyperechoic hepatic parenchyma. The differential is an endocrine-associated vacuolar hepatopathy such as the clinically reported diabetes melitus. A component of hepatic lipidosis may also be present.
4. echogenic urinary debris. Differentials include crystalluria, lipiduria, or cellular debris (hemorrage vs pyuria)
4. Fine Needle aspiration of the liver was performed, cytology results are pending and we will contact you in 2 to 3 business days with results.

In hospital treatments:
1. Provided with continuous IV fluids
2. We gave injectable anti-nausea medication as well as pain medication
3. We monitored his blood sugar level
1. His Blood Glucose was not consistently/ persistently >15mmol/L, therefore we did not start him back on insulin (I will chart on his SS the numbers they gave me)

Medications to go home
-discontinue Atopica
-gabapentin - give 0.9ml by mouth every 8 to 12 hours for pain, may cause mild sedation.
-marbofloxacin- give 1 by mouth every 24 hours with food until finished. Antibiotic.
-Mirtazapine- Give 1/4 of a tablet by mouth every 24 hours as an appetite stimulant.
Aventi Liver- Give 1/4 tab by mouth every 12 hours until finished. Liver detoxifying medication

Diet: daibetic diet, less than 7% carb content

Follow up: recheck blood glucose at home, 4-5 samples per day; note times he ate during the day. report info to regular vet and keep a close eye on thirst and urination (drinking more than 90ml/kg/day is considered excessive, appetite, vomitting, diarrhea

If he conitnues to have poor appetite, blood sugar is difficult to interpret, or you have any other concners, we recommend you recheck with your regular vet and also seek out an internet medicine consultation for further work up and diagnosis (she told me to do this asap to get on a wait list). Ideally recheck full bloodwork including urinalysis) in 10 days prior to discontinuing marbofloxacin

Monitoring: Please monitor for vomiting, diarrhea, not eating, tremors. If you notice any of these signs or have concerns, please contact ER or your vet
 
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Hi Charlene
I would definitely ask for antinausea meds as well as an appetite stimulant. Sir Thomas has to have had the nausea treated first before giving the appetite stimulant. So ask for some oral cerenia and ondansetron. They work on different pathways and can be given at the same time if needed. We can help you with that at home but you need to have the meds.
Also ask them to give him IMI cerenia before he comes home and that will last the first 24 hours at home.
He may well eat for you at home. Cats often will eat for their owners when they won’t eat for the vets. But unless the nausea has been addressed first you can’t expect him to want to eat.
Don’t be afraid of a feeding tube. They are very good at being able to get the necessary food into the cat and are not hard to deal with......I think much easier than syringe feeding.

I am still very concerned they are saying he is not a true diabetic. 11 is above the normal range for cats and still too high to go without insulin.
He may just need a very small amount of insulin. I hope they are testing daily for ketones.

All your questions are good.
Definitely get them to email you all the lab tests they have done s they are yours...you
Paid for them. And Marje can have a look at them.

I think when you get him home, give him a few hours to settle in and if his blood glucose is above the normal range, he needs insulin. Yes, cats can get stressed at the vet and their BG can go up, but it doesn’t usually stay up for days just due to stress.

I hope you have managed to get a good nights sleep.

Thank you so much.She said they were monitoring for DKA, but it didn't say much on the discharge notes but I will also keep monitoring with the at home strips. I asked for the anti-nausea, he is home as of this afternoon and acted as he was ravenous, sniffing all the food I put out (DM, fancy feast, friskies) but declining all when he smelled them. He will eat temptations treats and beg for them (that is an improvement from before but not sure if he should really be eating those) and he ate about 40 cals of a fillet treat. He also really wanted to eat my cheese off my plate but no go on every kind of fancy feast, friskas and DM. It was weird because he acted hungry eating the treats.


I agree with Bron on the anti nausea meds.

I wonder if his elevated liver enzymes are due to hepatic lipidosis. I would ask. I would also ask about the gallbladder & bile duct and how do they know unequivocally. Ask if they did a bile acids assay. I would also ask if this could be cholangiohepatitis or triaditis although I suspect they will say “no” since they think the gallbladder is not involved. Ask if he is jaundiced.

Likely they will give Denamarin for liver support. It’s a coated pill you cannot cut and has to be given on an empty tummy. I prefer just giving milk thistle which I buy in powder form from Chewys if they ship there. I use Herbsmith which you can mix with a small amount of chicken or turkey baby food with no onions, garlic, broth and syringe feed if he will let you.

i don’t know what they mean by his kidneys were not great but not diseased. Makes no sense. Be sure you get copies of all labs and tag me. I’ll look at the kidney stuff, too.

Sending healing light!

Thank you so much for your input, the vet said it is not classic fatty liver, but they will find out more when they get results. They said they did a bile acidsessay (SP???) to rule out fall bladder and bile duct issues. He is also not jaundiced. She said when I redo my bloodwork it might be helpful to ask for a feline comprehensive geriatric screen.

I am still worried about him not eating. I am going to get another internal medicine specialist referral tomorrow for follow up. They also agreed that they would not have started him at 3 and never go up more than 1 unit at a time, just as you guys said as well.
 
I will tag @Marje and Gracie to comment on the vet report.
Did you manage to get the latest lab results from the ER vets?

It looks as if they did not give you any antinausea medications to bring him....do you know if they gave him a cerenia injection before discharge..
Acting hungry and sniffing then walking away are classic nausea signs in a cat.
Can you ring your regular vet and ask for some cerenia and or ondansetron?
They do mention a component of hepatic lipidosis may also be present (this occurs when the cat is not eating enough food ....cats must eat) so the treatment for that is food and plenty of it.
Is it is really important that he starts to eat .....another reason to get those antinausea medications. Don’t just leave it and wait and see. I would get onto it now.
I would let him eat whatever he will eat at the moment. It doesn’t matter if it is suitable for a diabetic cat or not at the moment because eating anything at all trumps everything else.

Keep monitoring the BG and the ketones and updating the SS please.
Sending lots of cuddles to Sir Thomas
 
Keytones negative today:)

Finallly got an anti-nausea prescribed, by a third covering vet and they will call me tonight when it is ready to pick up

Sugars are up again but i think the plan is food trial first, but i cant do that if he only will eat treats so hopefully this helps!
 
I agree with Bron on the anti nausea meds.

I wonder if his elevated liver enzymes are due to hepatic lipidosis. I would ask. I would also ask about the gallbladder & bile duct and how do they know unequivocally. Ask if they did a bile acids assay. I would also ask if this could be cholangiohepatitis or triaditis although I suspect they will say “no” since they think the gallbladder is not involved. Ask if he is jaundiced.

Likely they will give Denamarin for liver support. It’s a coated pill you cannot cut and has to be given on an empty tummy. I prefer just giving milk thistle which I buy in powder form from Chewys if they ship there. I use Herbsmith which you can mix with a small amount of chicken or turkey baby food with no onions, garlic, broth and syringe feed if he will let you.

i don’t know what they mean by his kidneys were not great but not diseased. Makes no sense. Be sure you get copies of all labs and tag me. I’ll look at the kidney stuff, too.

Sending healing light!
Yes the kidneys not great comment was strange. But the fact that they said he would get kidney disease within five years indicates to me that his SDMA was elevated.
 
Keytones negative today:)

Finallly got an anti-nausea prescribed, by a third covering vet and they will call me tonight when it is ready to pick up

Sugars are up again but i think the plan is food trial first, but i cant do that if he only will eat treats so hopefully this helps!
So glad you got anti-nausea meds. I can’t understand why it is so hard to pry this stuff out of vets ... especially Ondansetron since it’s the best darn anti-nausea med out there for cats. My vet originally tried to give me Reglan, which is not great and can have some nasty side effects.
 
There doesn’t appear to be an SDMA and I believe they were making this assumption from looking at his kidneys via U/S.

They said although his kidneys also were in the normal range, the tends looking at all his bloodwork over the years is pointing to worsening kidney health at a greater rate than would be contributed with age. They also did say the ultrasound was consistent with that too. I am going to start another thread today and I will link :)
 
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