Hi, Elmo has been on compounded PZI from pharmacy, U100, yes U100 this is the way the pharmacy makes it. Does anyone else use U100 compounded PZI??? Anway he was on 1 unit and changed diet to all canned. Not much change in BG after a week or so so switched to 1 and 1/2 units and only very slight decrease in BGs. Increased to 2 units and he has been on 2 units for about 8 days now. pre shot bg 360 gave 2 units +4 326 +6 312 +8 240 +10 220 pre shot +12 -317, gave 2 units he eats in am after shot and pm after shot ( usually 6am and 6pm) and then again at 10 or 11pm. Thanks so much input is much appreciated.