The light of my life, my Oscar, was diagnosed with diabetes two months ago. He was started on 2U of insulin twice a day (Lantus). I did home monitoring as best as he would allow me to (he has one testable ear, the other had a hematoma)...and had to bring him to the vet every week for checks. We also changed his diet to canned food (MD). At first, the insulin appeared to help, though it's been creeping up. More vet trips...increase in dosage to 3U twice a day. During this time, he's doing well, eating normally, urinating a lot...but we got his water consumption under control (6 ounces per day). He's been playing and very happy...and looking very good. Over the past two weeks, his appetite shrank to about 85-90% of what it had been. We thought that it might be due to the weather warming up...but had the vet run a glucose curve last Thursday. His scores were consistently over 400 with a high over 500. So...we increased the insulin dosage to 4U twice a day (again, as of last Thursday). Saturday, he started throwing up (big time). Into the vet (fortunately, they are open). IV, anti-vomiting meds and a blood screen that makes the vet suspect liver disease. Home with instructions that if he doesn't eat, go to the Pet Emergency. He eats a little Saturday...stops Saturday night and by Sunday morning, he is in bad shape. Into the Emergency Clinic we go. Ultrasound done Monday. No cancer or growths (hooray!), but liver is aggravated (almost "glows" on the image). He stays with the vet Monday. She has me try him at home yesterday afternoon...with instructions to try and get him to eat. He won't. She gave me AD food and a syringe to force feed him and try and jump start his appetite. No luck; as of this morning he won't eat. We're going back to the vet in an hour. Yesterday, he looked good after all the IV and special meds, but he's pretty drained now. Yesterday, he was so tired of the vet, but doing well enough that he pushed his nose against the cage until it swelled up...and pawed at the thing until his little feet got raw. That he won't eat is a vicious circle as I can't give him his insulin and he can't continue down that road. I guess we'll know a little more after we see the vet. Of course, she is willing to go as far as we are...but between the cost and his unhappiness/suffering, we can't go as far as she can. It's getting really hard now. We're $2k into this in 4 days and it doesn't look like we're winning. While the vet mentioned the possibility of a feeding tube to us yesterday, my wife is vehemently opposed to that. For me, Oscar is the most magical little buddy in the world. I can't even begin to tell you how special he is to my wife and I. I love him with every fiber of my heart and would gladly take the disease for him if I could. My wife is at her wits end. We can't let him suffer. This is completely wrenching my heart out of my chest. We feel so powerless. We are talking about putting him to sleep...and even the discussion is just chewing my soul to shreds. While I was typing this, he looked up at me from his bed (which he loves) and the look on his face of "Dad, I feel so drained." has this old bear of a man in tears. I literally don't know what to do. We lost an older cat (she was 14) just back in March. We lost another great buddy (he was about 15) literally a year before (to cancer, we think...the previous vet...that we no longer see...never could figure out what was wrong with him or how to treat it). Emotionally, these losses are still very fresh to us...and I guess we're feeling quite "raw" since the wounds haven't healed. Sorry to go on like this...it's just that there aren't a lot of people that love cats the way that I do and I figured that you folks probably feel much the same. Come the end of the day...or tomorrow, the worst thing may be where we end up. God help us.