Jill & Alex (GA)
Very Active Member
The Tight Regulation Protocol with Lantus or Levemir describes what we've fondly dubbed "New Dose Wonkiness" (NDW) here in the Lantus, Levemir, & Biosimilars ISG:
"Many cats will occasionally react to an increased dose with increased BGs - within the first 2 to 3 days after an increase, usually lasting for less than 24 hours. Nobody really knows what the reason for this phenomenon is (perhaps a "panicky liver"?) - hold the dose and ignore the fluctuations."
You might also see this happening while following the Start Low, Go Slow Method.
NOTE:
"Many cats will occasionally react to an increased dose with increased BGs - within the first 2 to 3 days after an increase, usually lasting for less than 24 hours. Nobody really knows what the reason for this phenomenon is (perhaps a "panicky liver"?) - hold the dose and ignore the fluctuations."
You might also see this happening while following the Start Low, Go Slow Method.
NOTE:
- NDW usually lasts for less than 24 hours and is usually seen in the second day following a dose increase.
- The concept of "New Dose Wonkiness" is NOT applied to higher numbers which may be seen after a dose reduction.
- There is no "NDW" following a dose reduction nor do we hold a reduced dose 6 cycles (as done with dose increases) to "fill the insulin depot".
- "Settling time" does not apply to dose reductions. We don't wait for a reduction to "settle".
- For those following the Tight Regulation Protocol: "If the cat will not stay in the normal range after a reduction, immediately increase the dose again to the last good dose."
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