So I know the rule of thumb, as far as I've read, is that if a cat has a blood sugar reading below 200, then it's safer to not give a shot. I've held to this rule so far, but the problem is that every time I skip Ziggy's shot due to low numbers, he zooms up to the 400s or 500s within the next couple of hours, and he has to suffer with that until his next test. I'm wondering if I could possibly give him a tiny shot if his numbers are between 150 and 200? For background: right now he's on a range between 3.75U and 4.25U (the former for when he has lower readings, the latter for higher readings) and both values bring him down quite a lot, though he's never gone below 50. If anything, 3.75U has helped him stay between 100 and 250 lately. Any thoughts on whether I could give him a tiny shot -- maybe .25U -- when he's between 150 and 200, just so he doesn't have to endure high numbers throughout the day/night?