Yum is at 5 units with pink nadirs. I will probably increase her dose tomorrow morning after 4 cycles. I am debating increasing by .5 units or 1 unit. If people are advised to increase by a quarter unit at 1 unit, a quarter of 5 units is greater than 1 unit. So is 5 units big enough to merit a 1 unit increase? I know I will probably be told to wait and do the increase after 6 cycles, but I need to get her back into safe territory. I did read the sticky on the depot just now. It does say depot effects can be more dramatic at higher doses. I need to read that sticky a few more times. Of course, mostly she has smooth curves. She has just been too high for too long. I will probably have her tested for IAA and Acro next week. I want her to go 14 days at least between blood draws. @Marje and Gracie . @Wendy&Neko (I don't really know how to tag people. Maybe that didn't work.) I also read the sticky on early and late doses just now, as I was thinking about her numbers while she was boarded at the vet over Christmas and when she first came home last Wednesday. I guess those yellows and blues were due to early doses. I think the clinic probably dosed her at least 2 hours early in the evenings. I dosed her an hour early for her first 2 shots at home. Since I stopped early dosing she hasn't seen yellow. Kind of makes me want to shoot her at an 11 hour interval, but I know that isn't how it works. Is it?