The recommended dose on the Zobaline container says 3mg once daily. I've read that most cat owners give this for approx. 3 months until the neuropathy is improved. Does anyone here who has a diabetic cat with CKD continue to give Zobaline at that dose? I've been reading that a CKD cat should not be given over .5 mg of methyl-b12 a day to prevent toxicity since the kidneys are not sufficiently functioning. My cat is diabetic and CKD and did well on Zobaline but I reduced the dose and he is limping now. I don't know if that could be attributed to the reduction of the vitamin supplement or something else.