8/21 Uncle 372, +2 295, +6 224, PMPS 208, +4 181

Discussion in 'Lantus / Levemir / Biosimilars' started by Barbara & Uncle (GA), Aug 21, 2017.

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  1. Barbara & Uncle (GA)

    Barbara & Uncle (GA) Well-Known Member

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    Oct 13, 2016
    http://www.felinediabetes.com/FDMB/...30-6-46-6-5-86-7-5-114-pmps-200-3-223.182504/

    I haven't posted in a couple of days. Uncle's numbers have been out of control and he's not feeling well.
    His cardiologist had recommended that I double the Sotalol dose on Friday , because his ECG results showed only a little improvement in the arrhythmia. So I did that for a couple of doses and 24 hours later he didn't want to eat and had a bout of diarrhea. He has had a terrible appetite since. I think it is nausea because he will look interested, take a few bites, run away and hide in the closet.
    I spoke with my vet first thing this morning, she relayed the info to the cardiologist and he said:

    "These are HIGHLY unusual and unexpected side effects. But, is it impossible? Of course not.
    Let’s STOP the medication for 24 hours, then resume at 1 mg/kg PO q12h for several days, see how he is doing, and then we can try to go to 1.5 mg/kg PO q12h (assuming this is liquid compounded). We absolutely can start any/all necessary GI meds (Cerenia and Metronidazole) to help recover the appetite faster.
    I suspect this is unrelated, but would rather default to a side effect than another problem. Please let me know if you have any questions!"

    It's already been 36 hours of no Sotalol and not much has improved but I did pick up some Cerenia fron the vets this afternoon. I am to give him half of a 16 mg tab once daily. Hope it helps, in the meantime I don't realy want to give him anything else except that and his insulin.
     
  2. Wendy&Neko

    Wendy&Neko Senior Member Moderator

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    Feb 28, 2012
    Sorry for the rough weekend.:bighug::bighug: Inappetence can be a side effects of heart conditions. That was Neko's first clue something was off with her. You might want to see if you can get a prescription for ondansetron too. I found it worked better for Neko. ECID. Cerenia and ondansetron target different nausea receptors so one may work better than the other. I hope Uncle feels better soon.
     
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  3. carfurby (GA)

    carfurby (GA) Well-Known Member

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    Feb 19, 2012
    I hope the meds help and Uncle feels better soon. Sending prayers. :bighug::bighug::bighug::bighug::bighug::bighug::bighug:
     
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  4. Chubba (GA)

    Chubba (GA) Well-Known Member

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    Apr 30, 2017
    Feel better soon Uncle. :bighug::bighug:
     
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  5. Bronx's dad (GA)

    Bronx's dad (GA) Well-Known Member

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    Nov 30, 2016
    Hope the Cerenia helps Uncle
     
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  6. Squalliesmom

    Squalliesmom Well-Known Member

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    Jun 26, 2015
    Sending prayers and good appy vines. I hope Uncle feels better soon! (((Hugs))) :bighug::bighug::bighug:
     
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  7. Bron and Sheba (GA)

    Bron and Sheba (GA) Well-Known Member

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    Feb 21, 2015
    I am sorry Uncle is not feeling well. I hope he starts to feel better soon and feels like eating
    Sending lots of feel better and hungry vines
    :bighug::bighug::bighug:
     
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  8. Chris & China (GA)

    Chris & China (GA) Well-Known Member

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    May 10, 2013
    Awww...sorry to hear Uncle's been feeling pretty puny, but hopefully the Cerenia will do the trick!

    It's nice to hear your vet be so concerned about fixing the problem even if he doesn't believe it's being caused by the medication!

    Sending mega vines your way Uncle!!
    [​IMG]
     
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  9. Barbara & Uncle (GA)

    Barbara & Uncle (GA) Well-Known Member

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    Oct 13, 2016
    Yes, I feel lucky to have vets that are more open minded about that stuff. It's all hard enough already, so not having to push against their advice is a really nice break!
     
  10. Barbara & Uncle (GA)

    Barbara & Uncle (GA) Well-Known Member

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    Oct 13, 2016
    Good to know, I will see how/if the Cerenia makes a difference and ask for Ondansetron if not. He's really getting bony :(
     
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