Hello Acro Folks! I've been weighing testing my Amber for acromegaly (and IAA of course, while I'm at it, but mostly the acro), and I wanted to put the case to you guys (because I figure you've been in the trenches and know the condition far better than most vets!). I might just be grasping at straws here. Question first, then the details. Is it possible for an acro tumor to behave in the following way: pulse on briefly, inducing a short period of insulin dependence, go dormant for an extended period (1.5yrs), then turn back on again? Or does that long an OTJ period make an acro diagnosis really unlikely? Details: Amber's on her second go-round with insulin. First time around, she zipped pretty quickly down the dosing ladder to remission, and then spent a year and a half in excellent numbers (generally 50's-70's). The FD came back with a bang-- essentially overnight, she was back up in the 200's. Now, we've been on insulin for a few months again, and she's gone far higher on the dosing ladder (4.25U, Lantus) than she ever was before, with absolutely no sign of any physical problems. No infection, no pancreatitis flares, she just had a dental last week that revealed no issues other than a "tip fracture" that was (according to x-rays) surface-only and not causing any pain. There have been hints along the way this time of stepwise changes in insulin needs-- see early-mid April, when she looked like she was poised to go back down the dosing ladder from 2.0U, then suddenly started signalling she actually wanted more...). In addition to her current high (-ish) dose, there's at least one physical symptom that might point to acro. She's always snored a bit, but it seems like lately she's snoring a lot, it's quite noticably more pronounced. Hmmm...... So that's why I'm starting to think of things like acro, even if it's jumping the gun in terms of her current dose. But does it even seem like a likely diagnosis given her history, or am I being silly? What do you think?